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Growth Factors And Epilepsy

Price: 88.54 USD

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Product Details

Author Name: Binder, Devin K.; Scharfman, Helen E.

Binding: Hardcover

Book Condition: Very Good

Type Book

Publisher Hauppauge, New York, U.S.A. Nova Science Pub Inc 2005

ISBN Number 1594544212 / 9781594544217

Seller ID 005428

No interior writing or highlighting. Slight scuffing. Growth Factors And Epilepsy By Binder, Devin K.; Scharfman, Helen E. Product Details The discovery that a variety of growth factors modulate excitability in the adult brain, and that the expression of growth factors and their receptors are often modulated by seizure activity, has opened an exciting new chapter in epilepsy research. Recent findings shed new light on these and other ways growth factor neurobiology impacts epilepsy research, including the role of growth factors in seizure-induced neurogenesis, kindling, and morphological changes that contribute to the epileptic phenotype. In addition to neurotrophins such as brain-derived neurotrophic factor, and the p75 and trk receptors for neurotrophins, recent studies also implicate vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and glial cell line-derived neurotrophic factor (GDNF) in seizure-induced structural and functional changes. The current volume highlights seminal contributions to this field by renowned scientists in both the growth factor and epilepsy research fields. Preface; Seizure-induced neurogenesis in the dentate gyrus and its dependence on growth factors and cytokines; Neurotrophins, kindling, and kindling-induced morphological changes in the brain; Multiple actions of brain-derived neurotrophic factor on central neurons; Accumulation of BDNF in the dendrites: a link with epileptogenesis?; Seizure and the p75 neurotrophin receptor: death by design?; Immunohistochemical analysis of trk receptor activation in epilepsy; VEGF as a novel seizure therapeutic: killing two birds with one stone; Fibroblast growth factors and seizure-induced neuroprotection; The GDNF family of neurotrophic factors and epilepsy; Running away from epilepsy: exercise regulated gene expression Hardcover: 237 pages Publisher: Nova Science Publishers (September 12, 2005) Language: English ISBN-10: 1594544212 ISBN-13: 978-1594544217 Product Dimensions: 1 x 7.5 x 10.5 inches

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